Other Roles
Lead scientist for Barts Health
HDR-UK Real World Evidence Network Co-lead of Surgery and Perioperative medicine working group
OHDSI global community
Honorary Clinical Lecturer, Barts Health
about
Jenny
MA MEd DPhil FRCS(Tr & Orth)
Jenny is a NIHR Academic Clinical Lecturer leading collaborative big data research at Barts as she completes her training in Orthopaedic Surgery. Working within the OHDSI data science community, she uses large routinely collected datasets to improve our understanding of surgical treatments and the use of surgical devices.
Jenny leads Barts Health in the new UK Real-World Evidence Network established by HDR-UK, working with the MHRA, NICE and NHS England to improve surveillance of devices and drug use in the UK. She is establishing international networks of surgeons to undertake multi-centre federated network analyses in big data, particularly focussed upon projects to generate evidence for underrepresented communities and rare orthopaedic diseases by combining Barts Health data with global partners.
Jenny undertook her PhD in Musculoskeletal Sciences at the University of Oxford and was funded by Versus Arthritis Clinical Research and MRC Doctoral Training Fellowships for this work. She focussed on the epidemiology of hand conditions which is now quoted in NHS guidelines for patients. During the Covid-19 pandemic she was also a core member of an international group of researchers investigating emerging pandemic treatments that changed national policies in Europe and the US.
Jenny studied undergraduate medicine at Exeter College, Oxford and undertook basic medical and surgical training in London. She graduated with distinction from Masters of Surgical Education at Imperial College, London and began training in Academic Orthopaedic surgery as a NIHR Academic Clinical Fellow in Oxford in 2014.
She lectures for the Masters in Surgical Science & Practice and DPhil in Musculoskeletal Sciences, University of Oxford. Outside of surgery, she spends her time as head chef and playdate social secretary to her 2 young sons.
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Current Studies
Mapping the FFN international collaboration of hip fracture registries to the OMOP data model
The EHDEN public private project was set up under the framework of IMI2, with twenty-two partners, including academia, SMEs, patient associations, regulatory authorities and pharmaceutical companies, led by Erasmus Medical Centre, The Netherlands, and Janssen Pharmaceutica N.V., Belgium.
Publications
Key
Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study
Lane JCE, Weaver J, Kostka K, Duarte-Salles T, et al. (OHDSI Covid-19 collaboration: senior authors Prieto-Alhambra D and Ryan P).Lancet Rheumatology 2020 Nov;2(11):e698-711. PMID:32864627
Serious postoperative complications and reoperation after carpal tunnel decompression surgery in England: a nationwide cohort analysis
Lane JCE, Craig RS, Rees JL, Gardiner MD, Green J, Prieto-Alhambra D, Furniss D.
Serious adverse events and lifetime risk of reoperation after elective shoulder replacement: population based cohort study using hospital episode statistics for England
Craig RS, Lane JCE, Carr AJ, Furniss D, Collins GS, Rees JL. BMJ 2019. Feb 20;364:I298. PMID: 30786996
Use of repurposed and adjuvant drugs in hospital patients with covid-19: multinational network cohort study
Albert Prats-Uribe, Anthony G Sena, Lana Yin Hui Lai, Waheed-Ul-Rahman Ahmed, Heba Alghoul, Osaid Alser, Thamir M Alshammari , Carlos Areia et al.
LATEST
Serious adverse event rates and reoperation after arthroscopic shoulder surgery: population based cohort study
JL Rees, R Craig, N Nagra, M Baldwin, JCE Lane, A Price, DJ Beard et al. BMJ 2022;378:e069901
Preschool Obesity Is Associated With an Increased Risk of Childhood Fracture: A Longitudinal Cohort Study of 466,997 Children and Up to 11 Years of Follow-up in Catalonia, Spain
Jennifer CE Lane,Katherine L Butler,Jose Luis Poveda-Marina,Daniel Martinez-Laguna,Carlen Reyes,Jeroen de Bont,Muhammad Kassim Javaid,Jennifer Logue,Juliet E Compston,Cyrus Cooper,Talita Duarte-Salles,Dominic Furniss,Daniel Prieto-Alhambra
Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study.
Edward Burn, Seng Chan You, Anthony G. Sena, Kristin Kostka, Hamed Abedtash, Maria Tereza F. Abrahão, Amanda Alberga, Heba Alghoul, Osaid Alser et al.
Development and external validation of prediction models for adverse health outcomes in rheumatoid arthritis: A multinational real-world cohort analysis
Cynthia Yang, Ross D.Williams, Joel N.Swerdel, João Rafael Almeida, Emily S.Brouwer, Edward Burn, Loreto Carmona, Katerina Chatzidionysiou et al.
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